Black Walnut

Published on December 20, 2025 by Guy

Black Walnut (Juglans nigra) is a North American tree whose green hulls have been used for centuries as a powerful antiparasitic and antifungal remedy. The hulls contain juglone, a compound with potent antimicrobial properties that must contact infected tissue directly to be effective. Traditional uses span from expelling intestinal parasites to treating ringworm and athlete's foot, and it remains popular today for addressing gut dysbiosis and fungal infections.

Effects and Benefits

Core Identification

Common Names:
- Black Walnut
- American Walnut
- Eastern Black Walnut

Latin Name: Juglans nigra

Category: Herb

Uses

Traditional Uses

  • Intestinal parasite expulsion (tapeworm, threadworm, giardia) - Native American and early American folk medicine
  • Fungal skin infections (ringworm, athlete's foot) - Cherokee and European herbal traditions
  • Skin conditions (eczema, herpes, psoriasis, scrofulous diseases) - Eclectic medicine, 19th century
  • Wound healing and difficult sores - Cherokee medicine (bark wash "to kill the poison")
  • Constipation and intestinal toxemia - Traditional American herbalism

Modern Uses

  • Intestinal parasites - Used for tapeworms, giardia, and other intestinal parasites | Research quality: Preliminary
  • Key findings: Juglone demonstrates antiparasitic activity; traditionally combined with other antiparasitic herbs
  • Source citations: Easley - The Modern Herbal Dispensatory; Coffman - Herbal Medic

  • Fungal infections - Athlete's foot, ringworm, candida, nail fungus | Research quality: Moderate

  • Key findings: Juglone has documented antifungal properties; topical application most effective
  • Source citations: WRCHM - Western Materia Medica II; Gladstar - Herbal Recipes for Vibrant Health

  • Gut dysbiosis and SIBO - Addresses bacterial overgrowth in digestive tract | Research quality: Preliminary

  • Key findings: Locally-acting antimicrobial that must contact infected tissue
  • Source citations: WRCHM - Western Materia Medica II

  • Thyroid support - Contains iodine for hypothyroid conditions | Research quality: Preliminary

  • Key findings: Natural iodine content may support thyroid function; also supports gut bacteria regulation
  • Source citations: Garrett - The Cherokee Herbal

Active Compounds

Primary Active Ingredients:
- Juglone - Primary medicinal constituent with antifungal and antiparasitic activity; alcohol-soluble, poorly water-soluble
- Tannins - Provide astringent properties for wound healing and tissue toning
- Iodine - Natural antiseptic; supports thyroid function
- Selenium - Trace mineral with antioxidant properties

Dosage Information

Standard Dosage:
- Form: Tincture
- Amount: 5 drops to 1 ml
- Frequency: Three times daily

Therapeutic Dosage:
- Tincture (fresh hulls 1:2, 95% alcohol): 1-3 ml, three times daily
- Tincture (dried hulls 1:5, 50% alcohol): 1-3 ml, three times daily
- Glycerite (dried hulls 1:6): 1-5 ml, three times daily
- Capsules/Powder: 1,000-2,000 mg, three times daily
- Duration: 2-3 weeks maximum, then take an equivalent break

Maximum Safe Dosage:
- Daily maximum: 9 ml tincture or 6,000 mg powder
- Warning threshold: Do not exceed 3 weeks continuous use without a break

Bioavailability Notes:
- Juglone is alcohol-soluble but poorly water-soluble; tinctures preferred over teas
- Fresh green hulls produce stronger medicine than dried
- Must contact infected tissue directly for antimicrobial effect

How to Take It

Timing:
- Take between meals for parasite cleansing
- Can be taken with food if stomach upset occurs
- Best used as part of a broader protocol, not as a standalone long-term remedy

Synergies - What It Works Well With

Complementary Supplements:
1. Wormwood (Artemisia) - Classic combination for parasite protocols | Enhanced antiparasitic effect
2. Clove - Traditional trio with black walnut and wormwood | Targets parasite eggs
3. Pau d'Arco - Combined for antifungal formulas | Broader antifungal spectrum
4. Oregano - Antifungal formula companion | Complementary antimicrobial mechanisms
5. Neem - Used together for foot/nail fungus (with red henna) | Enhanced topical antifungal effect

Avoidance - What NOT to Combine With

Supplement Interactions:
1. High-iodine supplements - May cause iodine excess | Potential thyroid disruption

Drug Interactions:
1. Blood pressure medications - May potentiate effects | Monitor blood pressure | Severity: Moderate
2. Thyroid medications - Iodine content may interfere | Consult healthcare provider | Severity: Moderate
3. Sedatives - Large doses have sedative effects on circulation | May enhance sedation | Severity: Mild

Food Interactions:
- None specifically documented
- Take separately from mineral supplements to avoid absorption interference

Safety Information

Contraindications:
- Pregnancy - not recommended
- Lactation - reduces milk production; avoid unless this effect is desired
- Dry constitutions or emaciation
- Weak digestion
- Kidney disease (use cautiously)
- Heart disease (use cautiously)
- Do NOT use for deworming horses - toxic to equines

Side Effects:
- Skin staining (will turn skin, nails, clothing black - use gloves)
- Fresh green husks can cause skin irritation or blistering in excessive quantities
- Large internal doses may have sedative effects on circulation and heart
- Possible allergic reactions during pollen season (May)

Long-Term Use:
- Not recommended for extended continuous use
- Cycle: 2-3 weeks on, then equivalent break period
- Best used as part of a formula rather than alone
- Should be administered by trained professionals for internal use

Special Precautions:
- Always use gloves when handling fresh hulls
- Will permanently stain fabrics, towels, and surfaces
- For topical neti pot use: Add 30 drops tincture to normal saline, let stand 25 minutes before use

Primary Uses At-a-Glance

Primary: Intestinal parasites, fungal infections (ringworm, athlete's foot, candida), gut dysbiosis

Secondary: Skin conditions (eczema, psoriasis), thyroid support, wound healing, constipation

Sources

Local Library:
- Easley, Thomas - The Modern Herbal Dispensatory
- Coffman, Sam - Herbal Medic
- WRCHM - Western Materia Medica II
- Tourles, Stephanie L. - Hands-On Healing Remedies
- Gladstar, Rosemary - Herbal Recipes for Vibrant Health
- Pursell, J. J. - The Herbal Apothecary
- Lust, John - The Herb Book
- Garrett, J. T. - The Cherokee Herbal

General Knowledge:
- Traditional Eclectic medicine texts (Felter)
- General herbalism training data